Inflammation and Parkinson's disease pathogenesis
Identifieur interne : 001C23 ( Main/Exploration ); précédent : 001C22; suivant : 001C24Inflammation and Parkinson's disease pathogenesis
Auteurs : Serge Przedborski [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 2010.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Animals, Cyclooxygenase 2 (metabolism), Disease Models, Animal, Dopamine (metabolism), Humans, Inflammation, Inflammation (metabolism), Inflammation (pathology), MPTP, Nervous system diseases, Neuroglia (physiology), Parkinson Disease (metabolism), Parkinson Disease (pathology), Parkinson disease, Parkinson's disease, Pathogenesis, inflammation.
- MESH :
- chemical , metabolism : Cyclooxygenase 2, Dopamine.
- metabolism : Inflammation, Parkinson Disease.
- pathology : Inflammation, Parkinson Disease.
- physiology : Neuroglia.
- Animals, Disease Models, Animal, Humans.
Abstract
Inflammation is a neuropathological feature of parkinsonian brains and also in experimental models of the disease. It is believed that activated glial cells, which compose the majority of this inflammatory response contribute to the neurodegenerative process through the production of toxic molecules. Therapeutic strategies geared toward reducing inflammation and inhibiting the production of these glial‐derived toxic molecules may be a promising neuroprotective strategy for the treatment of Parkinson's disease and related conditions. © 2010 Movement Disorder Society
Url:
DOI: 10.1002/mds.22638
Affiliations:
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Le document en format XML
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It is believed that activated glial cells, which compose the majority of this inflammatory response contribute to the neurodegenerative process through the production of toxic molecules. Therapeutic strategies geared toward reducing inflammation and inhibiting the production of these glial‐derived toxic molecules may be a promising neuroprotective strategy for the treatment of Parkinson's disease and related conditions. © 2010 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>États-Unis</li></country><region><li>État de New York</li></region><settlement><li>New York</li></settlement><orgName><li>Université Columbia</li></orgName></list><tree><country name="États-Unis"><region name="État de New York"><name sortKey="Przedborski, Serge" sort="Przedborski, Serge" uniqKey="Przedborski S" first="Serge" last="Przedborski">Serge Przedborski</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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